I was diagnosed with Parkinson's in Nov 2008, but up until three months ago, many of the symptoms have gotten much worse; my speech is very much impaired, when the medication wears off, I have a shortness of breath and I am quite constipated. I don't really know what meds to take as my doctor hasn't been overly helpful. I am now taking 2 Senimets 200/50 and one Comtan every three hours and seem to be getting shorter as the meds wear off. There are other meds out there but may not be available in Canada.The escalating part is kind of scary? Is the constsipation slowing down the effectiveness of the Senimet. Any help you can give me will be very much sppreciated.