logo
flag   
Responsive Navigation
Keyword Search: in
Niacin: Can It Help Your Cardio Health
View article disclaimer and terms

This article has been viewed 11120 times.
Ask us a Question
Name
Email Address
Comments
Code ^

More than 50 years of research indicates that niacin can help lower your triglycerides, raise your HDL cholesterol (good cholesterol), improve your circulation, and lower your LDL cholesterol, including Lipoprotein A. These effects are likely to positively support weight management. It has long been known that niacin helps widen your blood vessels which helps relax your arteries, thereby improving your circulation. This finding, along with its ability to promote healthier levels of blood fats and cholesterol has sparked considerable interest in its potential for cardiovascular health. One long term study showed that niacin reduced mortality by 11%.

Niacin intake also produces undesirable side effects that stop many people from using it. These include an irritating flushing effect, upset stomach, excessive skin itching, potential liver toxicity (in very high doses), and possibly raising blood sugar (in very high doses). None of these undesirable effects of niacin have not been reported with a safe and effective non-flushing form of niacin called inositol hexanicotinate (IHN). This enables you to get the benefits of niacin without the risks.

How Niacin Works

Your cellular engines (mitochondria) convert food to energy (ATP) through a complex process of many steps, similar to a production line in a factory. When someone on the production line is not functioning up to par it affects everything else down the line. Niacin is the backbone of two key enzymes (workers on the production line) known as NAD (nicotinamide adenine dinucleotide) and NADP (nicotinamide adenine dinucleotide phosphate) who perform an important role in how your cells make energy. They are also team players, helping as many as 200 other energy-related enzymes do their work. The ability of your body to break down fats, carbohydrates, and proteins and use them to make energy is dependent on having adequate niacin.

These niacin-containing enzymes play many other roles in your body, including assisting your DNA to repair itself when damaged. Niacin is especially active in your circulatory system. The inositol hexanicotinate form of niacin has been shown to help serious circulation problems like Raynaud’s disease (fingers turning blue upon cold exposure) and Intermittent Claudication (poor circulation to calf muscles when walking).

The classic severe niacin deficiency disease is called Pellagra. The symptoms included a scaly and darkly pigmented rash, vomiting, diarrhea, and dementia - a problem that often results in death. The common theme of all these symptoms is that blood does not flow to the affected body organ. Pellagra is not common in the U.S. and has historically appeared during times of famine.

More subtle deficiencies of niacin, which are involve energetic problems and circulation issues show up as:
• Fatigue and weakness (as niacin is needed by energy-producing enzymes).
• Skin problems (may be a factor in acne, rashes, dermatitis or psoriasis as a result of reduced blood flow to the skin).
• Poor appetite, bright red tongue, and/or diarrhea (poor blood flow to digestive tract).
• Mood stability issues, irritability, memory problems, and/or headaches (poor blood flow to the head).

Pellagra is prevented with 11 mgs of niacin per day, and this need is the basis for our government’s recommended amounts of this nutrient (20 mg per day). Since many of the symptoms on the above list are caused by other factors, it is often difficult to assign them to just niacin. However, increasing your intake of niacin may improve any of the issues on the above list by enhancing your circulation or energy production.

This review discusses the use of much higher amounts of niacin that have been shown to enhance metabolism and support cardiovascular health. Researchers have found that niacin intake far above levels that relate to Pellagra issues may have positive metabolic effects on cholesterol, triglycerides, and circulation.

HDL Cholesterol

HDL cholesterol is called good cholesterol. You need it in adequate amounts to haul LDL back to your liver, like a tow truck. It will also remove LDL cholesterol from your arterial walls and bring it back to your liver for elimination. If your levels of HDL are low then LDL levels elevate in your blood and are more likely to be damaged. This damaged LDL cholesterol is more likely to form plaque and without enough HDL there is no easy way to remove it from your arteries.

Niacin works to raise your HDL cholesterol levels by a very unique method of action, selectively telling your liver not to break down HDL so fast. It also increases the amount of helpful small particles of cholesterol that comprise HDL, including the very important ApoA1. ApoA1 is needed to energize HDL so it can effectively do its job, which includes anti-inflammatory and antioxidant effects on the walls of your arteries. Niacin is the most effective compound known for boosting HDL cholesterol and ApoA1.

LDL Cholesterol, Triglycerides, and Weight Loss

At the same time niacin helps to raise your good cholesterol it helps to naturally reduce the formation of LDL cholesterol. Studies show that inositol hexanicotinate (IHN) reduces the liver’s synthesis of VLDL cholesterol (very low density lipoprotein), in turn reducing the synthesis of LDL cholesterol. Your LDL contains the highest amount of cholesterol, your HDL contains the highest amount of protein, while your VLDL contains the highest amount of triglycerides. Because your VLDL is built of LDL particles, like Lipoprotein A (an LDL with a protein attached), the net result of lowering VLDL synthesis is to reduce both LDL and Lipoprotein A. This is a good thing because too much Lipoprotein A interferes with how your body dissolves clots in your circulation, meaning that if your Lipoprotein A levels are too high you’re more likely to have an increased risk for stroke. Niacin’s effect on cholesterol is highly cardiovascular protective.

Niacin not only reduces the triglyceride-rich VLDL it also reduces the free floating triglycerides in your circulation. It should be pointed out that VLDL is a main way that triglycerides are transported to your stored fat and dropped off. This means that high levels of VLDL are an indicator that weight gain is taking place. It is now recognized that higher levels of triglycerides in your blood are a major signal for worsening cardiovascular health. These triglyceride “fat blobs” form traffic jams that push up your blood pressure and reduce the correct entry of leptin into your brain, in turn producing leptin resistance and setting the stage for insulin resistance. Niacin’s nifty way of reducing triglyceride levels has the net result of being helpful in terms of reducing leptin problems and supporting weight management.

LDL cholesterol, while often called bad because it can end up in the walls of your arteries if it is damaged, is actually vital for transporting fat-soluble nutrition around your body (including your fat-soluble antioxidants). A major component of LDL and VLDL is a cholesterol particle called ApoB. The higher the amount of ApoB in the LDL or VLDL the smaller and denser is the size of the LDL or VLDL, the easier it is damaged, and the more likely it is to form plaque. Niacin helps change the make-up of LDL and VLDL so that there is less ApoB on board. It replaces it with a higher level of triglyceride-containing cholesterol particles, which in turn are lighter and more buoyant. These more buoyant LDL and VLDL particles are much less likely to be damaged or to form plaque. Of course, having fat soluble antioxidants on your LDL (like tocotrienols, carotenes, vitamin K, and Q10) offer further synergistic protection for your LDL or VLDL, helping to reduce the damage that may lead to plaque formation.

There are many ways to help lower triglycerides, beginning with the Five Rules of the Leptin Diet. Exercise also helps clear triglycerides by using them for fuel in your muscles. Likewise, there are a variety of healthy metabolic strategies to help lower cholesterol in a safe and effective way, with diet and exercise as your foundation. IHC’s novel method of reducing LDL synthesis will work synergistically with other nutrient strategies to help improve cholesterol fitness and cardiovascular health. For example, DHA fish oil is known to help lower triglycerides while promoting arterial flexibility and health, citrus extracts (like tangeretin and nobiletin) are known to help reduce levels of ApoB and triglycerides, lower LDL and boost HDL, tocotrienols lower LDL as well as protect it and the lining of your arteries, and pantethine helps lower triglycerides and LDL by transporting them better in metabolism. There are many synergistic angles to this equation, and IHC is one more tool in the metabolic toolbox that favors healthy metabolism of calories and better cardiovascular health.

What Kind of Niacin and How Much to Take

I prefer the form of no-flush niacin called inositol hexanicotinate (IHN). This is a slow release form niacin comprised of six molecules of niacin bound to one molecule of inositol. As it is metabolized niacin levels gradually rise, peaking about 10 hours after ingestion. In Europe this form of niacin is sold as a prescription (Hexopal) and has been extensively tested for safety up to doses of 4,000 mgs per day. There are no reports of liver problems from this form of niacin and it does not cause a flush.

The niacin flush and upset stomach that are so common in other forms of niacin cause many people not to take niacin who may benefit. The niacin flush triggers mast cells to release chemicals, and constantly doing this is not likely to be beneficial. Our new understanding of mast cells, linking nerves, immunity, and behavior, indicates that constantly triggering them is likely to have multiple undesirable side effects that have not currently been assigned to niacin.

In addition to the IHN form of niacin there is also a fast release type and an extended release type sold as a prescription (Niaspan) and often used in combination with statin drugs. Both of these types induce the niacin flush that is undesirable. High doses of these forms of niacin (above 4000 mg) have been associated with liver problems and in some cases slightly elevating blood sugar. These more significant problems are seldom seen with these forms of niacin in doses from 2,000 - 3,000 mg a day.

It is prudent for anyone taking any form of niacin to take it along with a liver protecting herb such as Milk Thistle (silymarin) simply to be on the safe side. And if a person has elevated liver enzymes or another liver problem then higher niacin intake is not a good choice.

In general, a dose from 1200 mg - 1800 mg a day is likely to help circulation, boost HDL, and improve the condition of LDL (make it more buoyant). Higher doses, up to 4000 mg a day, can be used to help lower LDL. Niacin can be divided into two or more doses a day, with one dose in the morning and another at bed (helps fat metabolism while sleeping).




By Byron J Richards CCN
All rights reserved. Any reproducing of this article must have the author name and all the links intact.

Byron J Richards CCN

Author:

Biography: Byron J. Richards, Founder/Director of Wellness Resources, Inc., is a Board-Certified Clinical Nutritionist and a world renowned natural health expert. He has been a charter professional member of the International and American Associations of Clinical Nutritionists (IAACN) since 1991.

ALSO VIEW OUR
Articles
(Total : 160)
  Title
Sort by Title A-Z
Sort by Title Z-A
A Healthy Lymph System is Vital for Flu Fighting Immunity
A Path Back From Addiction & Mental Health Problems
Abnormal Brain Structure in Schizophrenia
ADHD Linked to Early Life Instability & Sleep Problems
Alpha GPC for Focus, Memory, and Cognitive Ability
An Emerging Fiber Breakthrough for Weight Management
Another Thyroid Risk: Did Your Mom Smoke While Pregnant?
Antidepressants Strongly Linked to Heart Disease
Are Vaccinations Causing Early Alzheimer’s?
At What Point Does Pleasure Become Psychopathic?
Avandia is Killing Americans, FDA Negligence Comes Front and Center
BAMLET AND HAMLET – A New Play or a Cure for Cancer?
BDNF Prevents and Reverses Alzheimer’s Disease
Berries for Brain Protection
Big Brother Will Be Watching Your Weight
Big Pharma & Friends Poised for Massive Profits from Health Care Reform
Blood Pressure Therapy Called Into Question
Bone Drugs Cause Serious Atrial Fibrillation
Bone Drugs Proven to Cause Poor Bone Quality in Humans
Bone Health Can Help Prevent Obesity and Type 2 Diabetes
Brave Oxford Researchers Say Tamiflu is Not for Kids
Can High Good Cholesterol Be the Sign of a Problem?
Can Vitamin D Help Prevent H1N1 Swine Flu from Spreading?
Candida Problems Evolving
Citizens Win Huge Supreme Court Victory over Big Pharma and the FDA
Coenzyme Q10, Statins, and Heart Health
Cold Weather Mood Shock: Avoid the Winter Blues
Common Phthalate Exposure Linked to ADHD
Common Traits of the Long Lived
Curcumin: Linking Leptin, Obesity, Joint Problems, and Inflammation
Desperate Big Pharma Push to Double Statin Sales
DHA Protects Circulation from Dietary Abuse
DHA vs. Diabetes Drugs – Did You Balance Your PPAR Gamma Today?
DHA, Krill Oil & Green-Lipped Mussel – Which is Best?
DHEA Helps Older Women Build Spinal Bone Density
Dietary Supplements for Weight Loss
Exercise Tips for Fighting the Swine Flu
Fisetin for Neuro-Protection
Fish Oil in the Battle Against Depression & Cognitive Decline
Fish Oil Supplements Reduce Invasive Breast Cancer Risk by 32%
Flawed SELECT Study Attacks Vitamin E
Folic Acid and Vitamin D Help Allergies and Asthma
Friendly Flora Inhibits Bilirubin-Induced Digestive Damage
Friendly Flora Supplements Essential During Pregnancy & Nursing
Gamma Tocotrienol in the War on Cancer
Glial Cell Function Vital for Learning
Glutamine Helps Stomach Ulcers
Grape Seed Extract Restores Insulin Sensitivity
Guar Gum: The Fiber with a Swagger
Hayflick Comments on Aging
Health Costs Relating to Obesity Skyrocket
Health Scandal of the Decade – Monsanto’s GMO Perversion of Food
High Intake of EPA/DHA Reduces Risks for Cardiovascular Disease
High-Fat Diet May Adversely Alter Your Brain Structure
How Bad Fat Programs Future Generations to Be Obese
How Hostile Bacteria Take Up Unwanted Residence
How Imbalanced Digestive Bacteria Cause Obesity & Heart Disease
How PCBs Damage the Developing Brain
How the FDA, Big Pharma, and Doctors Cause Injury for Profit
hyroid Problems, Alzheimer’s, and Cognitive Decline
Immunometabolism: The New Frontier
Introducing the Wellness Resources Daily Prenatal Multi Vitamin
Is Itching a Risk Factor for Cancer?
Is Obama Bailing Out Big Pharma’s Bursting Bubble?
Is There Hope for Glenn Beck’s Eyes?
Jump Start Your Weight Loss in 2009
Laughable Type II Diabetes Research Shines Light on Medical Ineptitude
Leptin Now Directly Linked to the Pleasure of Food & Human Behavior
Low Iron Can Cause Chronic Pain
Low Vitamin C Impairs Early Brain Development
Low Vitamin D Contributes to Thyroid Problems
Mainstream Sounding Alarms on Alternative Thyroid Treatments
Major Blood Pressure Discovery Offers Immediate Solutions
Mass-Produced Meat and Chicken Contaminated with MRSA Superbug
Massive Brain Drugging of Children Now Underway
Maximizing DHA Intake Supports Weight Loss
McCain’s Anti-Supplement Bill Appears Dead – For Now
Michael Jackson is Not Alone
Monsanto’s Toxic and Mutated World – Is Sugar Safe to Eat?
More Proof that Statins Damage Muscles in Many People Taking Them
MRSA Threatens World Health
Natural Dietary Supplements for Weight Loss
New Insights on Addiction, Mood, Memory, and Cognitive Ability
New Science Questions Theory of Antidepressant Drugs
New Strain of Superbug Rapidly Spreading Around the World
Niacin: Can It Help Your Cardio Health?
Niacinamide Turns Out To Be a Potent Candida-Killing Nutrient
Noni as a Natural Immune Booster
Obama Tries to Sneak Major Health Care Reform into the Stimulus Bill
Obesity and the Path to Heart Disease
Obesity Trend Out of Control
Olive Leaf Extract Offsets Stress of High Calorie Intake
Omega 3 Fatty Acids Prevent Serious Mental Health Problems
Omega 3 Oils Slow Aging by Preserving Telomeres
Oprah’s Crazy Talk – Bioidentical Hormones – Helpful or Harmful? (Part 1)
Oprah’s Thyroid Problem Explained
Oprah’s Weight Is National News – Again
Oprah’s “Crazy Talk" – Bioidentical Hormones – Helpful or Harmful? (Part 2)
Overweight People Need Extra Antioxidants for Exercise
Pantethine – Boost Your Brain, Cardio Health, Metabolism, and Detoxification
Paula Deen's Deception for Profit
Poor Response to Exercise in Young Type 2 Diabetics
Potassium Offsets Salt-Induced Cardiovascular Distress
Pregnancy Cautions: Caffeine, Stress, & Depression.
Pregnant Women at Higher Risk for Severe Swine Flu
Prostate Cancer & the Androgen Receptor – A Clearer Picture of the Problem
Prostate Cancer and Zinc – Can Zinc Be Overdone?
Quality Fish Oil
Quercetin as an Anti-Cancer Nutrient
Quercetin Reduces Pain, Anxiety, and Depression
Quercetin: A Rising Star for Nerves, Immunity, and Metabolism
Scientists Document How Coumadin Increases Disease Risk
Sirtuin1 During Calorie Restriction – Application for Weight Management
Six Months of Smoking is Adequate for Significant Brain Damage
Snacking is Damaging Health; Mrs. Obama is Off Target
Startling Evidence of Brain Decay at Age 39
Statin Use Speeds Onset of Coronary Adverse Event Hospitalizations
Statins Impair Immune System Function
Steep Escalation in Minority Obesity and Breast Cancer
Steve Jobs’ Wasting-Away Health Problem
Surprisingly High Cancer Risk from CT Scans
Swine Flu Tip – Don’t Be Your Own Petri Dish
Talk About Pulling The Plug On Grandma
Tamiflu Causes Delirium and Suicide in Children
Tamoxifen Shockingly Found to Cause Aggressive Breast Cancer
Teen Sleep Problems Lead to Depression & Drug Abuse
The Addictive Nature of Compulsive Eating
The Amazing New World of HDL Cholesterol
The Colorful History of Colloidal Silver & Other Silver Compounds
The Effects of Green Tea on Weight Management
The Facts on Magnesium Stearate
The Failure Empire: Bob Greene Rakes It In, Oprah Fails
The FDA’s Peramivir H1N1 Swine Flu Experiment
The Highly Pathogenic E. Coli Genie is Out of the Bottle – Can You Withstand an Attack?
The Narrow Scope of Flu Vaccine Usefulness
The New Flu Vaccine Hype is Over-Rated
The New Role of Glucosamine in Human Health
The Poorly Developing ADHD Brain
The Swine Flu – Are Pigs to Blame?
The Top 10 Health Breakthroughs of 2008
Theanine – A Nutrient for Relaxation
Thyroid, Adrenals, & Immunity – A Clear Path to Surviving Swine Flu
Thyroid-Disrupting Triclosan Jumps Into the Frying Pan
Tips for Cardiovascular Health
Tocotrienols: Twenty Years of Dazzling Cardiovascular and Cancer Research
Top Thyroid Stories of the Past Year
Using Nutrition to Help Perceive and Combat Swine Flu
Utilizing Quality Calcium for Health
Vitamin D is Needed to Fight and Prevent the Flu
Vitamin D – A Gene-Regulating Super Nutrient
Vitamin E Protects Lungs from Damage
Vitamin K Reduces the Risk for Non-Hodgkin Lymphoma
Vitamin K2: Bones, Cardiovascular Health, Blood Sugar Control & Cancer Prevention
Was Giuliana Rancic’s Breast Cancer Caused by IVF?
What Are Your Baby Fat Cells Doing?
What is Leptin?
What is the Leptin Diet?
What’s in Your Multiple Vitamin? Minerals, Detecting Real Quality.
Which Whey to Go
Will Drinking Milk Help You Live Longer?
Products & Equipment
(Total: 66)
  Title
Sort by Title A-Z
Sort by Title Z-A


Contact Form

Please use this form to contact Byron J Richards
** This form is intended for those with genuine enquiries/questions.
 

Name
Company (if any)
Comments
Email
Phone
  To avoid misuse and spamming, please enter the verification code, shown below, to send your message. Thank you
 
if you can't read the image text to load another one.
Enter Code
 

Disclaimer and Terms. This article is the opinion of the author. WorldwideHealth.com makes no claims regarding this information. WorldwideHealth.com recommends that all medical conditions should be treated by a physician competent in treating that particular condition. WorldwideHealth.com takes no responsibility for customers choosing to treat themselves. Your use of this information is at your own risk. Your use of this information is governed by WWH terms and conditions.